Analyzing WGBS with the bsseq package

نویسنده

  • Kasper Daniel Hansen
چکیده

This document discusses the ins and outs of an analysis of a whole-genome shotgun bisulfite sequencing (WGBS) dataset, using the BSmooth algorithm, which was first used in [1] and more formally presented and evaluated in [2]. The intention with the document is to focus on analysis-related tasks and questions. Basic usage of the bsseq package is covered in “The bsseq user’s guide”. It may be useful to consult the user’s guide while reading this analysis guide.

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تاریخ انتشار 2013